Non-invasive Prenatal Test

What is the NIPT test？

NIPT is a non-invasive prenatal test, meaning it is completely safe for pregnant women and fetuses. As with any other routine blood analysis, a small blood sample taken from the arm can be tested. NIPT uses the latest NGS technology to extract fetal free DNA from pregnant women's blood to detect specific abnormalities with high accuracy and reliability.

Those pregnant women recommend doing NIPT

Suitable

1. Pregnant women who are more than 10 weeks pregnant and concerned about the health of their fetus.
2. High-risk group of chromosomal abnormalities: elderly mothers, family history, fetuses with chromosomal abnormalities, abnormal ultrasound detection and suspected fetal chromosomal abnormalities, and people at high risk of Down syndrome
3. Those who are not suitable for invasive prenatal diagnosis: placenta previa, oligohydramnios, unstable fetal condition, stable bleeding, persistent bleeding,
4. Worries about the risk of invasive prenatal diagnosis (such as amniocentesis, chorionic sampling, etc.)

Those pregnant women are not recommended to do NIPT

1. High-risk pregnant women: such as elderly women, high Down's screening, abnormal fetal ultrasound, and chromosomal abnormalities, etc., because the National Health Administration has subsidized a chromosome test fee of 5,000 yuan, it is recommended to directly receive amniocentesis chromosome examination To confirm the condition of the fetus.
2. Pregnant women with twins or multiples
3. Pregnant women with atrophied embryos who undergo artificial conception during the same pregnancy
4. Pregnancy weeks are less than 10 weeks
5. Pregnant women are overweight (over 80 kg)
6. Pregnant women who have just received blood transfusion
7. Pregnant women themselves have chromosome variants (e.g. translocation type, mosaic type)
8. Worries about other chromosomal abnormalities or genetic abnormalities in the fetus

Product Description

The common clinical chromosomal abnormalities are 21-trisomy (Down's disease), 18-trisomy (Edward's disease), 13-trisomy (Battau's disease), sex chromosome trisomy and X-mono Body type (Turner's disease), abnormal chromosome fragments such as chromosome deletion / duplication. Although the chance of a fetal chromosomal abnormality increases with the age of the pregnant woman, a fetus with a chromosomal abnormality is not a patent for older mothers (35 years and older). According to statistics, 80% of fetuses with chromosomal abnormalities (common such as Down's disease) actually come from non-senior women. Therefore, general (under 34) pregnant women also need to be screened for prenatal chromosomal genes. The advantage of NIPT is that it is known earlier than the best 17 weeks of amniocentesis. Because only the venous blood of pregnant women is drawn, there is no need to bear the risk of abortion. Sequencing technology combined with global fetal chromosome database for comprehensive analysis. Mainly report on chromosomes 13 (Battau's disease), 18 (Edward's disease), 21 (Down's disease), sex chromosomal abnormalities and other chromosomal abnormalities. The accuracy rate is above 99% ~ 99.5%, which can replace the first and second stage of maternal Down's disease screening but not completely replace the amniocentesis. Because the amniocentesis can detect abnormalities of the chromosome structure in addition to the abnormal number of chromosomes However, the "basic" "non-invasive prenatal chromosome screening" only detects abnormalities in the number of chromosomes, and unless it is "intact", it can strengthen cat crying, chubby wiley disease, di Joe's disease and other tiny fragments are missing.